Use of new antiretroviral drugs and classes in Bahia, Brazil: a real life experience on salvage therapy of AIDS patients

Brazilian Journal of Infectious Diseases

Brites, Carlos¹  Nóbrega, Isabella¹  Netto, Eduardo Martins¹ 

[1] Universidade Federal da Bahia, Salvador, Brazil

关键词:  HIV;    Antiretroviral;    Salvage therapyOne of the most important problems in the treatment of HIV-1 infected patients has been the development of resistance to antiretroviral (ARV) drugs;   

DOI  :  10.1016/j.bjid.2015.03.005

来源: Contexto

【 摘 要 】

Antiretroviral therapy has significantly evolved in the last decade, with an increasing number of new drugs and classes. Currently, even heavily experienced patients can be successfully treated with new regimens. In Brazil, the recent incorporation of some new antiretroviral drugs made it possible to suppress HIV plasma viremia in most treated patients, with significant benefits in terms of quality of life and survival. However, little has been published on outcomes of patients under new drugs-based regimens. We reviewed the safety and efficacy of antiretroviral regimens using recently introduced drugs in Bahia. Our results confirm that patients using darunavir, raltegravir, enfuvirtide, or etravirine presented with a high rate of virological suppression without significant adverse events, after one year of follow-up.

【 授权许可】

Unknown