The use and interpretation of serum retinol distributions in evaluating the public health impact of vitamin A programmes

Public Health Nutrition

Nita Dalmiya¹  Werner Schultink¹  Keith P West¹  Amanda C Palmer¹ 

关键词: Vitamin A;    Deficiency;    Fortification;    Supplementation;    Assessment;   

DOI  :  10.1017/S1368980012000560

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

AbstractObjectiveDeveloping countries have adopted universal, high-potency vitamin A (VA) supplementation and food fortification as major strategies to control deficiency, prevent nutritional blindness and reduce child mortality. Yet questions persist regarding how best to measure impact and when to phase out supplementation. The present paper provides guidance on the use and interpretation of serum retinol (SROL) distributions as indicators of both programme impact and adequate VA intake in a population.DesignWe reviewed extant data on SROL's response to high-potency VA supplementation and VA-fortified foods in children.ResultsSupplementation virtually eliminates xerophthalmia and reduces child mortality; however, it shifts the SROL distribution only transiently (

【 授权许可】

Unknown