Phenotypic Analysis of Hepatic Lymphocytes from Healthy Dogs

Journal of Veterinary Medical Science

Atsuhiko HASEGAWA⁴  Toshihiro WATARI²  Manabu SAKAI²  Kiichi KANAYAMA³  Akira TAKEUCHI²  Tsuneo SATO¹  Isao OTANI³ 

[1] Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Nihon University;Laboratory of Comprehensive Veterinary Clinical Studies, Department of Veterinary Medicine, Nihon University;Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Nihon University;Laboratory of Veterinary Pathobiology, Department of Veterinary Medicine, Nihon University

关键词: liver;    lymphocyte;    phenotype;   

DOI  :  10.1292/jvms.65.157

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(13)Cited-By(2)Phenotypes of lymphocytes from laparoscopically biopsied liver tissues of eleven healthy beagle dogs were analyzed. The proportion of CD3+ lymphocytes (T cells), CD3 -CD21+ lymphocytes (B cells) and CD3 -CD21- lymphocytes (non-T non-B lymphocytes), and the CD4+/CD8+ ratio in the canine hepatic lymphocytes were 54.8 ± 11.9%, 4.7 ± 3.1%, 40.7 ± 13.2%, and 0.33 ± 0.12, respectively, while those in peripheral blood lymphocytes were 85.4 ± 6.5%, 9.3 ± 6.1%, 5.3 ± 1.8%, and 1.64 ± 0.36, respectively. These results indicated that the constitution of hepatic lymphocytes quite differed from that of peripheral blood lymphocytes in dogs, and suggested that the regional immunity in canine liver might be specific.

【 授权许可】

Unknown