Effect of extracts from Anethum graveolens, Melissa officinalis y Calendula officinalis on the human spermatozoa

Revista Cubana de Plantas Medicinales

Cadavid, Ángela¹  Arango, Víctor¹  Álvarez Gómez, Ángela¹  Cardona Duque, Daniela¹  Cardona Maya, Walter¹  Puerta Suárez, Jenniffer¹ 

[1] Universidad de Antioquia, Medellín, Colombia

关键词: Anethum graveolens;    Melissa officinalis;    Calendula officinalis;    spermicide;    saponins;    spermatozoa;    contraception;   

DOI  :  

学科分类：药理学

来源: Editorial Ciencias Medicas

【 摘 要 】

Introduction: there is wide availability of contraceptives; however unwanted pregnancy rate is not decreasing. One of the contraceptive methods employed are spermicides.Objective: the objective of this study was to evaluate the effect of extracts from three plants extract: Anethum graveolens L. (Apiaceae), Calendula officinalis L. (Asteraceae), and Melissa officinalis L. (Lamiaceae) on the motility and viability of the human spermatozoon. Methods: semen samples from healthy volunteers were incubated with each plant extract at different concentrations, and the effects on spermatozoon motility and viability were evaluated. Results: Anethum graveolens extract reduced motility and viability by 65.3 and 16 % (p< 0.05, 5 min vs. control), respectively; Melissa officinalis extract decreased motility by 78.2 % and viability by 22.3 % (p< 0.05, 5 min vs. control). Finally, Calendula officinalis extract reduced motility and viability by 55.3 and 48.4 %, respectively (p< 0.05, 5 min vs. control). Conclusions: none of the plant extracts at concentrations used in this assay has spermicidal effect on human sperm.

【 授权许可】

Unknown