Effects of Surgical Wound Infiltration with Bupivacaine on PostoperativeAnalgesia in Cats Undergoing Bilateral Mastectomy

Journal of Veterinary Medical Science

Esra KARACAM¹  Banu DOKUZEYLUL²  İsmail KIRŞAN¹  T. Seval Fatma TOYDEMIR¹  Zeynep GUNAY¹  Özge Turna YILMAZ¹ 

[1] Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Istanbul University, Avcılar, 34320, Istanbul, Turkey;Department of Internal Medicine, Faculty of Veterinary Medicine, Istanbul University, Avcılar, 34320, Istanbul, Turkey

关键词: bupivacaine;    carprofen;    feline;    pain;    radical mastectomy;   

DOI  :  10.1292/jvms.14-0112

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(33)The analgesic effect of woundinfiltration with bupivacaine was evaluated in cats undergoing bilateral mastectomy.Twenty-one female cats with mammary gland tumors were anesthetized with propofol andoxygen-isoflurane anesthesia following premedication with atropine. In the trial group(Group I; n=11), 30 ml of saline containing 2 mg/kg of bupivacaine wasinfiltrated topically into the surgical wound right after removal of the mammary glands,whereas only saline solution was infiltrated in the control group (Group II; n=10). At thesame time, carprofen (4 mg/kg) was also administered subcutaneously in both groups.Behavioral signs of pain were monitored during the recovery period after generalanesthesia. In order to examine the behavioral changes associated with acute pain, aquestionnaire was prepared and given to the owners to be completed 4 hr and then 10 hrafter the operation. According to the owners�? anwers to the questionnaire, a pain scorewas specified using a “numerical rating scale�? for each cat. Although some cats showedmild to moderate pain, the pain score recorded at 4 hr after the operation wassignificantly lower in Group I (P<0.001). No significant differencewas found at 10 hr after the operation between the groups. The incidence of vocalization,aggression and convulsion within 2 hr after the operation was also lower in Group I. Inconclusion, wound infiltration with bupivacaine before incisional closure providedreliable analgesia at least 4 hr after bilateral radical mastectomy in cats.

【 授权许可】

Unknown