Stable isotope dilution techniques for assessing vitamin A status and bioefficacy of provitamin A carotenoids in humans

Public Health Nutrition

Harold C Furr¹  Judy D Ribaya-Mercado¹  Emorn Wasantwisut¹  Sam Newton¹  Guangwen Tang¹  Marjorie Haskell¹  Najat Mokhtar¹  Sherry Tanumihardjo¹  Penelope Nestel¹  Michael H Green¹ 

关键词: Vitamin A;    Isotope dilution;    Vitamin A status;    Nutrition assessment;    Mathematical models;   

DOI  :  10.1079/PHN2004715

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

Vitamin A deficiency is a major global public health problem. Among the variety of techniques that are available for assessing human vitamin A status, evaluating the provitamin A nutritional values of foodstuffs and estimating human vitamin A requirements, isotope dilution provides the most accurate estimates. Although the relative expense of isotope dilution restricts its applications, it has an important function as the standard of reference for other techniques. Mathematical modelling plays an indispensable role in the interpretation of isotope dilution data. This review summarises recent applications of stable isotope methodology to determine human vitamin A status, estimate human vitamin A requirements, and calculate the bioconversion and bioefficacy of food carotenoids.

【 授权许可】

Unknown