Blood Gas Analysis in Dogs with Pulmonary Heartworm Disease

Journal of Veterinary Medical Science

Kyouji YASUDA¹  Hitoshi KITAGAWA¹  Yoshihide SASAKI¹ 

关键词: blood gas;    canine;    dirofilariasis;    heartworm removal;    pulmonary heartworm disease;   

DOI  :  10.1292/jvms.55.275

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(18)Cited-By(4)Blood gases were analyzed in dogs with pulmonary heartworm (HW) disease. The arterial oxygen tension (PaO2) in dogs with mild signs of dirofilariasis (mildly affected group, n=48, 85.7±8.2 mmHg) and in dogs with signs of right heart failure (severely affected group, n=13, 76.4±11.6 mmHg) was lower (p<0.01) than in dogs without HW infection (HW-free group, n=19, 91.5±7.3 mmHg). Only 2 dogs in the severely affected group had a PaO2 less than 60 mmHg. The arterial carbon dioxide tension (PaCO2, p<0.01) and mixed venous O2 (p<0.01) and CO2 (p<0.01) tensions were lower, and alveolar-arterial oxygen difference (AaDO2, p<0.01) was greater in the severely affected group than in the HW-free and mildly affected groups. Arterial pH and bicarbonate (HCO3-) concentrations were lower (p<0.01) in both affected groups than in the HW-free group. The anion gap level was not different among the 3 groups. Serum lactic acid level in the severely affected group was higher (p<0.01) than in the HW-free and mildly affected groups. However, a slightly higher serum lactic acid concentration was found only in 2 dogs of the severely affected group (3.84 mmol/l and 3.82 mmol/l). The PaO2 (r=-0.62) and AaDO2 (r=0.66) correlated significantly (p<0.01) with mean pulmonary arterial pressure. One week after HW removal, blood gases, pH and HCO3- concentration remained unchanged in the mildly affected group. In the severely affected group, blood gas values were the same, but pH and HCO3- concentration improved slightly.

【 授权许可】

Unknown