Self-reported dietary intake and appetite predict early treatment outcome among low-BMI adults initiating HIV treatment in sub-Saharan Africa

Public Health Nutrition

Meridith Blevins¹  Isaac Zulu¹  Douglas C Heimburger¹  Webster Kasongo¹  Bryan E Shepherd¹  Edmond K Kabagambe¹  John R Koethe¹  Albert Mwango¹  Christopher Nyirenda¹  Claire Bosire¹ 

关键词: HIV;    Malnutrition;    Antiretroviral therapy;    Africa;   

DOI  :  10.1017/S1368980012002960

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

ObjectiveLow BMI is a major risk factor for early mortality among HIV-infected persons starting antiretrovial therapy (ART) in sub-Saharan Africa and the common patient belief that antiretroviral medications produce distressing levels of hunger is a barrier to treatment adherence. We assessed relationships between appetite, dietary intake and treatment outcome 12 weeks after ART initiation among HIV-infected adults with advanced malnutrition and immunosuppression.DesignA prospective, observational cohort study. Dietary intake was assessed using a 24 h recall survey. The relationships of appetite, intake and treatment outcome were analysed using time-varying Cox models.SettingA public-sector HIV clinic in Lusaka, Zambia.SubjectsOne hundred and forty-two HIV-infected adults starting ART with BMI

【 授权许可】

Unknown