Revista Cubana de Plantas Medicinales | |
Effects of Maytenus macrocarpa (Ruiz & Pav.) Briq. (chuchuhuasi) in temperature, respiratory rate, heart rate, and electrocardiogram | |
Loja Herrera, Berta1  Huaccho Rojas, Juan Jesús1  Quezada Rojas, Melissa Andrea1  Lara Paredes, Andrea Mercedes1  Lluen Escobar, Silvana Estela1  Mujica Calderón, José1  Rojas Villacorta, Fernando Junior1  Alvarado Yarasca, Ángel1  Salazar Granara, Alberto1  Cavero Aguilar, Evelyn Sally1  Paragulla Bocángel, Ahmed Alberto1  | |
[1] Universidad de San Martín de Porres, Lima, Perú | |
关键词: Maytenus macrocarpa; chuchuhuasi; electrocardiogram; heart rate; respiratory rate; temperature; adrenaline; acetylcholine; atropine; propranolol; | |
DOI : | |
学科分类:药理学 | |
来源: Editorial Ciencias Medicas | |
【 摘 要 】
Introduction: studies on Maytenus trees comprising forsskaoliana, krukovii, and ilicifolia species showed depressing effects on the blood pressure and the heart rate. Objectives: to experimentally analyze the effects of Maytenus macrocarpa leaves on the heart rate, the electrocardiographic patterns, the respiratory rate, and the temperature. Method: this study was exploratory, analytical, and experimental. Albino rats were grouped in 9 groups of 8 rats each. Group 1 (control: Halatal), group 2 (placebo: distillated water), group 3 (adrenaline), group 4 (atropine), group 5 (acetylcholine), group 6 (propranolol), group 7 (500 mg/kg chuchuhuasi), group 8 (1 000 mg/kg chuchuhuasi), and group 9 (1 500 mg/kg chuchuhuasi). The rectal temperature was measured with a mercury thermometer, whereas the direct count allowed measuring the respiratory frequency. The polygraph registered electrocardiogram and heart rate as well. The MATLAB program analyzed data from the electrocardiogram. The statistic validation was performed with ANOVA, Tuc
【 授权许可】
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