Effects of Maytenus macrocarpa (Ruiz & Pav.) Briq. (chuchuhuasi) in temperature, respiratory rate, heart rate, and electrocardiogram

Revista Cubana de Plantas Medicinales

Loja Herrera, Berta¹  Huaccho Rojas, Juan Jesús¹  Quezada Rojas, Melissa Andrea¹  Lara Paredes, Andrea Mercedes¹  Lluen Escobar, Silvana Estela¹  Mujica Calderón, José¹  Rojas Villacorta, Fernando Junior¹  Alvarado Yarasca, Ángel¹  Salazar Granara, Alberto¹  Cavero Aguilar, Evelyn Sally¹  Paragulla Bocángel, Ahmed Alberto¹ 

[1] Universidad de San Martín de Porres, Lima, Perú

关键词: Maytenus macrocarpa;    chuchuhuasi;    electrocardiogram;    heart rate;    respiratory rate;    temperature;    adrenaline;    acetylcholine;    atropine;    propranolol;   

DOI  :  

学科分类：药理学

来源: Editorial Ciencias Medicas

【 摘 要 】

Introduction: studies on Maytenus trees comprising forsskaoliana, krukovii, and ilicifolia species showed depressing effects on the blood pressure and the heart rate. Objectives: to experimentally analyze the effects of Maytenus macrocarpa leaves on the heart rate, the electrocardiographic patterns, the respiratory rate, and the temperature. Method: this study was exploratory, analytical, and experimental. Albino rats were grouped in 9 groups of 8 rats each. Group 1 (control: Halatal), group 2 (placebo: distillated water), group 3 (adrenaline), group 4 (atropine), group 5 (acetylcholine), group 6 (propranolol), group 7 (500 mg/kg chuchuhuasi), group 8 (1 000 mg/kg chuchuhuasi), and group 9 (1 500 mg/kg chuchuhuasi). The rectal temperature was measured with a mercury thermometer, whereas the direct count allowed measuring the respiratory frequency. The polygraph registered electrocardiogram and heart rate as well. The MATLAB program analyzed data from the electrocardiogram. The statistic validation was performed with ANOVA, Tuc

【 授权许可】

Unknown