Vitamin D and risk of CVD: a review of the evidence

Proceedings of the Nutrition Society

Thomas A. B. Sanders¹  Catherine M. Fry¹ 

关键词: Ergocalciferol;    Cholecalciferol;    Cardiovascular risk;   

DOI  :  10.1017/S0029665115000014

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

This review summarises evidence for an association between vitamin D status and CVD and the mechanisms involved. Vitamin D3 is predominantly provided by the action of UVB from sunlight on skin. Average UK diets supply 2–3 μg/d vitamin D but diets containing at least one portion of oily fish per week supply about 7 μg/d. Pharmacological doses of vitamin D2 (bolus injection of 7500 μg or intakes >50 μg/d) result in a smaller increase in plasma 25(OH)D than those of D3 but physiological doses 5–25 μg/d seem equivalent. Plasma 25(OH)D concentrations are also influenced by clothing, obesity and skin pigmentation. Up to 40 % of the population have plasma 25(OH)D concentrations

【 授权许可】

Unknown