Genetic Analysis of an H5N2 Highly Pathogenic Avian Influenza Virus Isolatedfrom a Chicken in a Live Bird Market in Northern Vietnam in 2012

Journal of Veterinary Medical Science

Long van NGUYEN²  Hiroshi KIDA³  Kenji SAKURAI¹  Yoshihiro SAKODA³  Diep Nguyen THI²  Masatoshi OKAMATSU³  Nam van HOANG²  Huy Duc CHU²  Tatsuya NISHI³  Long Pham THANH² 

[1] OIE Regional Representation for Asia and the Pacific, Food Science Building 5F, The University of Tokyo, Tokyo 113�?8657, Japan;Ministry of Agriculture and Rural Development, 15/78 Giaiphong, Phuongmai, Dongda, Hanoi, Vietnam;Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060�?0818, Japan

关键词: avian influenza;    H5N2;    live bird market;    reassortant;    Vietnam;   

DOI  :  10.1292/jvms.13-0311

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(14)Cited-By(3)In August 2012, A/chicken/Vietnam/OIE-2215/2012 (H5N2) was isolated from achicken in a live bird market (LBM) in Northern Vietnam. Intravenous pathogenicity testrevealed that this virus is highly pathogenic in chickens. The PA, HA, NP and M, PB2 andNA, and PB1 and NS genes of the isolate were phylogenetically closely related to those ofA/duck/Vietnam/OIE-2202/2012 (H5N1) of clade 2.3.2.1, A/chicken/Vietnam/OIE-1611/2012(H9N2) and A/chicken/Vietnam/OIE-2468/2012 (H9N2), respectively. All of these viruses wereisolated from birds in LBMs in the same province. These results indicate thatA/chicken/Vietnam/OIE-2215/2012 (H5N2) is a genetic reassortant and that surveillance ofavian influenza in LBMs and stamping out policy are essential for the eradication ofhighly pathogenic avian influenza viruses from Asia.

【 授权许可】

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