Lack of Discrimination Against Non-proteinogenic Amino Acid Norvaline by Elongation Factor Tu from Escherichia coli

Croatica Chemica Acta

Cvetešić, Nevena¹  Gruić-Sovulj, Ita¹  Akmačić, Irena¹ 

[1] Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, HR-10000 Zagreb, Croatia

关键词: EF-Tu;    norvaline;    non-proteinogenic amino acids;    aminoacyl-tRNA synthetases;    leucyl-tRNA synthetase;    mistranslation;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

The GTP-bound form of elongation factor Tu (EF-Tu) brings aminoacylated tRNAs (aa-tRNA) to the A-site of the ribosome. EF-Tu binds all cognate elongator aa-tRNAs with highly similar affinities, and its weaker or tighter binding of...

【 授权许可】

Unknown