Mast Cell Sarcoma with Megakaryocytic Differentiation in a Calf

Journal of Veterinary Medical Science

Ayako FUJIMOTO¹  Yoshiharu ISHIKAWA²  Koichi KADOTA²  Toshiaki KANADA³  Yoshihiro WADA⁴ 

[1] Kamikawa Livestock Hygiene Service Center, 4–15 Higashitakasu, Asahikawa 071–8154, Japan;Hokkaido Research Station, National Institute of Animal Health, 4 Hitsujigaoka, Toyohira, Sapporo 062–0045, Japan;Saroma Veterinary Clinical Center, Okhotsk Agricultural Mutual Relief Association, 127–2 Nishitomi, Saroma 093–0504, Japan;Ishikari Livestock Hygiene Service Center, 3 Hitsujigaoka, Toyohira, Sapporo 062–0045, Japan

关键词: cattle;    epitheliotropism;    globule leukocyte;    mast cell sarcoma;   

DOI  :  10.1292/jvms.12-0236

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(20)Cited-By(2)A case of mast cell sarcoma in a 5-month-old Holstein female calf is described. Macroscopically, enlargement of the spleen, lymph nodes, tonsils and kidneys was noted, and there were tumor masses in the neck region and on the pleura and peritoneum. The pericardium and uterine and ureter walls were also involved by tumor. Most neoplastic cells had eosinophilic granules, which were metachromatic and positive for naphthol AS-D chloroacetate esterase and tryptase, whereas smaller numbers of cells were positive for factor VIII-related antigen, a marker of megakaryocytes. Some of the predominant type of these tumor cells were found within the epithelia of the lungs, tonsils, gastrointestinal tract, liver, ureters, urinary bladder and uterus. Their normal counterparts were considered to be globule leukocytes.

【 授权许可】

Unknown