Efficiently Activated Serine Analogue is Not Transferred to Yeast tRNASer

Croatica Chemica Acta

Cvetešić, Nevena¹  Gruić-Sovulj, Ita¹  Weygand-Đurašević, Ivana¹  Majsec, Kristina¹  Dulić, Morana¹  Jarić, Jelena¹ 

[1] Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia

关键词: serine hydroxamate;    seryl-tRNA synthetase;    tRNA;    transfer step;    amino acid activation;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

Covalent attachment of cognate amino acid to the cognate tRNA is a prerequisite for the faithful synthesis of proteins in the cell. Aminoacylation of tRNA, catalyzed by aminoacyl-tRNA synthetases (aaRSs), proceeds by a two-step reaction...

【 授权许可】

Unknown