A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals

eLife

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[1] Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, United States;Department of Medicine, University of Chicago, Chigcago, United States;Division of Internal Medicine, Oregon Health & Science University, Portland, United States;Knight Cancer Institute, Oregon Health & Science University, Portland, United States;Knight Cancer Institute, Oregon Health & Science University, Portland, United States;Department of Public Health and Preventive Medicine, Oregon Health & Science University, Portland, United States;Center for Health Care Ethics, Oregon Health & Science University, Portland, United States;Department of Medicine, Oregon Health & Science University, Portland, United States;School of Medicine, Oregon Health & Science University, Portland, United States;

关键词: low-value care;    medical reversal;    evidence-based medicine;    Human;   

DOI  :  10.7554/eLife.45183

来源: publisher

【 摘 要 】

10.7554/eLife.45183.001The ability to identify medical reversals and other low-value medical practices is an essential prerequisite for efforts to reduce spending on such practices. Through an analysis of more than 3000 randomized controlled trials (RCTs) published in three leading medical journals (the Journal of the American Medical Association, the Lancet, and the New England Journal of Medicine), we have identified 396 medical reversals. Most of the studies (92%) were conducted on populations in high-income counties, cardiovascular disease was the most common medical category (20%), and medication was the most common type of intervention (33%).

【 授权许可】

CC BY