Continuous Renal Replacement Therapy: Who, When, Why, and How

Chest: The Journal of Circulation, Respiration and Related Systems

Paul M. Palevsky^1,2¹  Srijan Tandukar^1² 

[1] Renal Section, Medical Service, VA Pittsburgh Healthcare System, Pittsburgh, PA^2;Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA^1

关键词: acute kidney injury;    continuous renal replacement therapy;    dialysis;    hemodialysis;    hemofiltration;    AKI;    acute kidney injury;    CRRT;    continuous renal replacement therapy;    CVVH;    continuous venovenous hemofiltration;    CVVHD;    continuous venovenous hemodialysis;    CVVHDF;    continuous venovenous hemodiafiltration;    IHD;    intermittent hemodialysis;    PIRRT;    prolonged intermittent renal replacement therapy;    RRT;    renal replacement therapy;    UFH;    unfractionated heparin;   

DOI  :  10.1016/j.chest.2018.09.004

学科分类：呼吸医学

来源: American College of Chest Physicians

【 摘 要 】

Continuous renal replacement therapy (CRRT) is commonly used to provide renal support for critically ill patients with acute kidney injury, particularly patients who are hemodynamically unstable. A variety of techniques that differ in their mode of solute clearance may be used, including continuous venovenous hemofiltration with predominantly convective solute clearance, continuous venovenous hemodialysis with predominantly diffusive solute clearance, and continuous venovenous hemodiafiltration, which combines both dialysis and hemofiltration. The present article compares CRRT with other modalities of renal support and reviews indications for initiation of renal replacement therapy, as well as dosing and technical aspects in the management of CRRT.

【 授权许可】

CC BY