Pure fruit juice and fruit consumption and the risk of CVD: the European Prospective Investigation into Cancer and Nutrition–Netherlands (EPIC-NL) study

The British Journal of Nutrition

Floor R. Scheffers^1^2^3¹  Martijn Verheus^3²  Jolanda M. A. Boer^4³  Yvonne T. van der Schouw^5⁴  W. M. Monique Verschuren^1^5⁵ 

[1] Center for Nutrition, Prevention and Health Services,National Institute for Public Health and the Environment (RIVM),PO Box 1, 3720 BA Bilthoven,The Netherlands,^1;Center for Nutrition, Prevention and Health Services,National Institute for Public Health and the Environment (RIVM),PO Box 1, 3720 BA Bilthoven,The Netherlands^4;Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht,Utrecht University,PO Box 85500, 3508 GA Utrecht,The Netherlands,^2;Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht,Utrecht University,PO Box 85500, 3508 GA Utrecht,The Netherlands^5;The Hague University of Applied Sciences,PO Box 13336, 2501 EH The Hague,The Netherlands^3

关键词: Pure fruit juice;    Fruit;    CVD;    CHD;    Stroke;    Dietary guidelines;    European Prospective Investigation into Cancer and Nutrition–Netherlands;   

DOI  :  10.1017/S0007114518003380

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

Dietary guidelines for pure fruit juice consumption differ between countries, regarding the question whether pure fruit juice is an acceptable alternative for fruit. Currently, little is known about pure fruit juice consumption and the risk of CVD. In this prospective cohort study, we studied the association of pure fruit juice and fruit consumption with the incidence of fatal and non-fatal CVD, CHD and stroke and investigated the differences in association with pure fruit juice consumption between low and high fruit consumers. A validated FFQ was used to estimate dietary intake of 34 560 participants (26·0 % men and 74·0 % women) aged 20–69 years from the European Prospective Investigation into Cancer and Nutrition–Netherlands study. Adjusted hazard ratios (HR) were estimated using Cox regression after average follow-up of 14·6 years. Compared with no consumption, pure fruit juice consumption up to 7 glasses/week – but not consumption of ≥8 glasses – was significantly associated with reduced risk of CVD and CHD, with HR from 0·83 (95 % CI 0·73, 0·95) to 0·88 (95 % CI 0·80, 0·97). Consumption of 1–4 and 4–8 glasses/week was significantly associated with lower risk of stroke with HR of 0·80 (95 % CI 0·64, 0·99) and 0·76 (95 % CI 0·61, 0·94), respectively. Associations did not differ considerably between low and high fruit consumers. The highest three quintiles of fruit consumption (≥121 g/d) were significantly associated with lower incidence of CVD, with HR of 0·87 (95 % CI 0·78, 0·97) and 0·88 (95 % CI 0·80, 0·98). In conclusion, although we observed favourable associations of moderate pure fruit juice consumption with CVD, for now consumption of whole fruit should be preferred because the evidence of the health benefits of fruit is more conclusive.

【 授权许可】

CC BY