Determinants of sleepiness in obstructive sleep apnea

Sleep

Van Dongen, Hans P A^5¹  Staley, Bethany^6²  Pack, Allan I^6³  Pack, Francis M^6⁴  Prasad, Bharati^1,2,3⁵  Maislin, Greg^6⁶  Steffen, Alana D^3,4⁷  Dinges, David F^6,8⁸  Strakovsky, Inna^7⁹ 

[1] Center for Narcolepsy, Sleep and Health Research, College of Nursing, University of Illinois at Chicago, Chicago, IL^3;Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA^6;Department of Biobehavioral Health Science, College of Nursing, University of Illinois at Chicago, Chicago, IL^9;Department of Health System Science, College of Nursing, University of Illinois at Chicago, Chicago, IL^4;Department of Medicine, Pulmonary, Critical Care, Sleep and Allergy, College of Medicine, University of Illinois at Chicago, Chicago, IL^1;Department of Psychiatry, Unit for Experimental Psychiatry, Division of Sleep and Chronobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA^8;Jesse Brown VA Medical Center, Chicago, IL^2;Office of Clinical Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA^7;Sleep and Performance Research Center, Washington State University, Spokane, WA^5

关键词: OSA;    OSA-clinical assessment;    home sleep apnea testing;    cytokines;    sleepiness;    vigilance;   

DOI  :  10.1093/sleep/zsx199

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

Study ObjectivesSignificant interindividual variability in sleepiness is observed in clinical populations with obstructive sleep apnea (OSA). This phenomenon is only partially explained by the apnea–hypopnea index (AHI). Understanding factors that lead to sleepiness is critical to effective management of patients with OSA. We examined demographic and other factors associated with sleepiness in OSA.

【 授权许可】

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