Cardiac autonomic activity during sleep in high-altitude resident children compared with lowland residents

Sleep

Motamedi, Shayan^5¹  Carroll, Annette^6²  Webster, Rebecca^8³  Hill, Catherine Mary^1,2,3⁴  Simpson, David^9⁶  Cellini, Nicola^4⁷  Heathcote, Kate^7⁸  Bucks, Romola Starr^3⁹ 

[1] Department of General Psychology, University of Padova, Veneto, Italy^4;Department of Mechanical Engineering, University of Southampton, UK^5;Department of Otolaryngology, Poole General Hospital, UK^7;Division of Clinical Experimental Sciences, Faculty of Medicine, University of Southampton, UK^1;Institute of Sound and Vibration Research, University of Southampton, UK^9;Laboratory for Cancer Medicine, Harry Perkins Institute of Medical Research and University of Western Australia Centre for Medical Research, Perth, Australia^8;School of Psychological Science, University of Western Australia, Perth, Australia^3;Sleep Disorders Unit, Canberra Hospital, Australia^6;Southampton Children’s Hospital Department of Sleep Medicine, Southampton, UK^2

关键词: apnea;    autonomic nervous system;    children;    high altitude;    hypobaric hypoxia;    heart-rate variability;    REM sleep;    very low-frequency power;   

DOI  :  10.1093/sleep/zsy181

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

Study ObjectivesWe aimed to characterize heart-rate variability (HRV) during sleep in Andean children native to high altitude (HA) compared with age, gender, and genetic ancestry-similar low-altitude (LA) children. We hypothesized that the hypoxic burden of sleep at HA could induce variation in HRV. As children have otherwise healthy cardiovascular systems, such alterations could provide early markers of later cardiovascular disease.

【 授权许可】

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