Melanin-concentrating hormone-expressing neurons adjust slow-wave sleep dynamics to catalyze paradoxical (REM) sleep

Sleep

Varin, Christophe^1,2¹  Luppi, Pierre-Hervé^1,2² 

[1] Centre de Recherche en Neurosciences de Lyon (CRNL), SLEEP Team, CNRS, INSERM, Lyon, France^1;Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France^2

关键词: melanin-concentrating hormone;    tuberal hypothalamus;    DREADD;    pharmacogenetics;    CNO;    REM sleep;    slow-wave sleep;   

DOI  :  10.1093/sleep/zsy068

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

Study ObjectivesExperimental studies over the last 15 years established a role in sleep of the tuberal hypothalamic neurons that express melanin-concentrating hormone (MCH). Controversies still remain regarding their actual contribution to both slow-wave sleep (SWS) and paradoxical sleep (PS also known as REM sleep) or PS alone.

【 授权许可】

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