Excessive daytime sleepiness and napping in cognitively normal adults: associations with subsequent amyloid deposition measured by PiB PET

Sleep

Wong, Dean F^5,6,7,8¹  Spira, Adam P^1,2,3²  Simonsick, Eleanor M^4³  An, Yang^4⁴  Wu, Mark N^5,6⁵  Owusu, Jocelynn T^1⁶  Ferrucci, Luigi^4⁷  Bilgel, Murat^4⁸ 

[1] Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD^8;Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD^1;Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD^5;Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD^2;Johns Hopkins Center on Aging and Health, Baltimore, MD^3;National Institute on Aging Intramural Research Program, Baltimore, MD^4;Russell H Morgan Department of Radiology, Division of Nuclear Medicine and Molecular Imaging/High Resolution Brain PET, Johns Hopkins School of Medicine, Baltimore, MD^7;Solomon Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD^6

关键词: aging;    biomarkers;    brain imaging;    epidemiology;    neurological disorders;    sleepiness;    napping;   

DOI  :  10.1093/sleep/zsy152

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

Study ObjectivesTo determine the association of excessive daytime sleepiness (EDS) and napping with subsequent brain β-amyloid (Aβ) deposition in cognitively normal persons.

【 授权许可】

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