Regional brain tissue changes and associations with disease severity in children with sleep-disordered breathing

Sleep

Nixon, Gillian M^1,2,4¹  Ditchfield, Michael^2,5²  Weichard, Aidan^1,2³  Roy, Bhaswati^3⁴  Davey, Margot J^1,2,4⁵  Tamanyan, Knarik^1,2⁶  Biggs, Sarah N^1,2⁷  Horne, Rosemary S C^1,2⁸  Walter, Lisa M^1,2⁹ 

[1] Brain Research Institute, University of California – Los Angeles, Los Angeles, CA^7;Department of Anesthesiology, University of California – Los Angeles, Los Angeles, CA^9;Department of Neurobiology, University of California – Los Angeles, Los Angeles, CA^6;Department of Paediatrics, Monash University, Melbourne, Australia^2;Department of Radiological Sciences, University of California – Los Angeles, Los Angeles, CA^8;Department of Radiology, Monash Children’s Hospital, Melbourne, Australia^5;Melbourne Children’s Sleep Centre, Monash Children’s Hospital, Melbourne, Australia^4;The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia^1;UCLA School of Nursing, University of California – Los Angeles, Los Angeles, CA^3

关键词: magnetic resonance imaging;    cognition;    mood;    autonomic;    diffusion tensor imaging;   

DOI  :  10.1093/sleep/zsx203

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

Study ObjectivesChildren with sleep-disordered breathing (SDB) exhibit behavioral, cognitive, and autonomic deficits, suggestive of neural injury. We assessed whether the tissue alterations resulted from acute or chronic processes, and whether alterations correlated with disease severity.

【 授权许可】

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