Repeated fine-needle aspiration cytology for the diagnosis and follow-up of thyroid nodules

Revista Brasileira de Otorrinolaringologia

Graciano, Agnaldo José¹  Fischer, Carlos Augusto²  Chone, Carlos Takahiro³ 

[1] Hospital São José, Joinville, Brazil;Serviços Integrados de Patologia, Joinville, Brazil;Universidade Estadual de Campinas, Campinas, Brazil

关键词: Thyroid gland;    Thyroid neoplasms;    Fine-needle biopsy;    Head and neck neoplasms.;   

DOI  :  10.1016/j.bjorl.2014.07.002

学科分类：医学（综合）

来源: Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial

【 摘 要 】

INTRODUCTION:The recently-proposed Bethesda reporting system has offered clinical recommendations for each category of reported thyroid cytology, including repeated fine-needle aspiration (FNA) for non-diagnostic and atypia/follicular lesions of undetermined significance, but there are no sound indications for repeated examination after an initial benign exam.OBJECTIVE:To investigate the clinical validity of repeated FNA in the management of patients with thyroid nodules.METHOD:The present study evaluated 412 consecutive patients who had repeated aspiration biopsies of thyroid nodules after an initial non-diagnostic, atypia/follicular lesion of undetermined significance, or benign cytology.RESULTS:The majority of patients were female (93.5%) ranging from 13 to 83 years. Non-diagnostic cytology was the most common indication for a repeated examination in 237 patients (57.5%), followed by benign (36.8%), and A/FLUS (5.6%) cytology. A repeated examination altered the initial diagnosis in 70.5% and 78.3% of the non-diagnostic and A/FLUS patients, respectively, whereas only 28.9% of patients with a benign cytology presented with a different diagnosis on a sequential FNA.CONCLUSIONS:Repeat FNA is a valuable procedure in cases with initial non-diagnostic or A/FLUS cytology, but its routine use for patients with an initial benign examination appears to not increase the expected likelihood of a malignant finding.

【 授权许可】

CC BY