Correlation between symptoms and course duration of upper aerodigestive tract cancer at early and advanced stages

Revista Brasileira de Otorrinolaringologia

Santos, Francis Balduino Guimarães¹  Vasconcelos-Raposo, Jose Jacinto Branco²  Figueiredo, Maria do Carmo Tolentino³ 

[1] UNIMONTES;UTAD, Portugal;Universidade Estadual de Montes Claros (UNIMONTES)

关键词: clinical course;    late diagnosis;    neoplasms of the head and neck;    primary prevention;    signs and symptoms.;   

DOI  :  10.5935/1808-8694.20130125

学科分类：医学（综合）

来源: Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial

【 摘 要 】

There still are many clinical and biological aspects of the natural history of cancer of the upper aerodigestive tract to be unveiled; which in Brazil is a direct consequence of the failure of systematic prevention and early diagnosis campaigns.OBJECTIVE:To analyze the signs and symptoms presented by patients with the disease at initial and advanced stages. Other variables such as disease duration, general and nutritional status were considered.METHOD:A historical cohort study with a cross-section involving 895 subjects with cancer of the upper aerodigestive tract.RESULTS:Clinical findings were not statistically correlated with disease progression, nor with the disease in early stages, but it showed rapid disease development.CONCLUSION:The results suggest a disease of insidious onset in the early stages and fast course afterwards. The long disease duration - greater than three months, was associated with worsening in general and nutritional states of patients.

【 授权许可】

CC BY