Plant-based synthesis of silver nanoparticles in Handelia trichophylla and their biological activities

Bulletin of Materials Science

HASAN ALI HOSSEINI^3¹  HASAN MOSAWEE^5²  MOHAMMAD SADEGH AMIRI^2³  MOHAMMAD EHSAN TAGHAVIZADEH YAZDI^1⁵  KIMIYA PAKRAVANAN^6⁶  MAJID DARROUDI^7,8⁷  REZA KAZEMI OSKUEE^4⁸ 

[1]Chemistry Department, Payame Noor University, Tehran 19395-4697, Iran^3

[2]Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran^5

[3]Department of Biology, Payame Noor University, Tehran, Iran^2

[4]Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran^8

[5]NanoBioelectrochemistry Research Center, Bam University of Medical Sciences, Bam, Iran^1

[6]Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad 9177948564, Iran^6

[7]Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran^7

[8]Targeted Drug Delivery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran^4

关键词: Silver nanoparticles;    biosynthesis;    Handelia trichophylla;    antibacterial;    cytotoxicity.;   

DOI  :  

Subject:71.9

来源: Indian Academy of Sciences

【 摘 要 】

In this research, silver nanoparticles (AgNPs) were prepared via a ‘green’ procedure using an aqueous extract of Handelia trichophylla. The formation of AgNPs was confirmed by its light brown colour. The AgNPs were formed in silver nitrate (1 mM) via a bioreduction process in spherically shaped NPs with a mean diameter in the range of 20–50 nm. Moreover, the green synthesized AgNPs seemed to demonstrate a higher antibacterial activity against human pathogenic bacteria. In addition, the in vitro cytotoxicity effect of biosynthesized AgNPs was also investigated, which was detected tobe up to 15.62 $\mu$gml$^{−1}$ in the treated Neuro2A cells. Low toxicity and high antibacterial activity of biosynthesized silvernanoparticles can be utilized in different biological, biomedical and industrial applications.

【 授权许可】

CC BY