Inflammaging in cervical and lumbar degenerated intervertebral discs: analysis of proinflammatory cytokine and TRP channel expression

European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Aleksandra Sadowska¹  Ermioni Touli²  Wolfgang Hitzl³ 

[1] ETH Zurich;Hirslanden Klinik St. Anna;Paracelsus Medical University

关键词: Cervical and lumbar discs;    Degenerative disc disease (DDD) and disc herniation (DH);    Inflammaging;    Inflammation;    Intervertebral disc;    Transient receptor potential (TRP) channel;   

DOI  :  10.1007/s00586-017-5360-8

学科分类：骨科学

来源: Springer

【 摘 要 】

PurposeTo investigate and compare the occurrence of inflammatory processes in the sites of disc degeneration in the lumbar and cervical spine by a gene array and subsequent qPCR and to investigate the mechanistic involvement of transient receptor potential channels TRPC6 and TRPV4.

【 授权许可】

CC BY