First report of the occurrence and whole-genome characterization of Edwardsiella tarda in the false killer whale (Pseudorca crassidens)

The Journal of Veterinary Medical Science

Kyunglee LEE¹  Hye Kwon KIM² 

[1] Cetacean Research Institute (CRI), National Institute of Fisheries Science (NIFS), Ulsan 44780, Republic of Korea;Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea

关键词: Edwardsiella tarda;    marine mammal;    pathogen;    virulence factor;   

DOI  :  10.1292/jvms.17-0590

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

Although several Edwardsiella tarda infections have been reported, its pathogenic role in marine mammals has not been investigated at the genome level. We investigated the genome of E. tarda strain KC-Pc-HB1, isolated from the false killer whale (Pseudorca crassidens) found bycaught in South Korea. The obtained genome was similar to that of human pathogenic E. tarda strains, but distinct from other Edwardsiella species. Although type III and VI secretion systems, which are essential for the virulence of other Edwardsiella species, were absent, several virulence-related genes involved in the pathogenesis of E. tarda were found in the genome. These results provide important insights into the E. tarda infecting marine mammals and give valuable information on potential virulence factors in this pathogen.

【 授权许可】

Unknown