Reviews in Urology | |
Prostate Biopsy Characteristics: A Comparison Between the Pre- and Post-2012 United States Preventive Services Task Force (USPSTF) Prostate Cancer Screening Guidelines | |
Vladimir Ioffe1  Ivelina Hristova2  Thomas Huebner3  Navin Shah4  | |
[1] 21 Century Oncology, Greenbelt, MD;American University, Washington, DC;Integrated Cellular and Molecular Diagnostics, Greenbelt, MD;Mid-Atlantic Urology Associates, Greenbelt, MD | |
关键词: Prostate cancer; PSA screening; United States Preventive Services Task Force; | |
DOI : 10.3909/riu0793 | |
学科分类:基础医学 | |
来源: MedReviews, LLC | |
【 摘 要 】
To compare prostate cancer (PCa) characteristics diagnosed by prostate biopsy (Pbx) in the 3 years before and after the 2012 United States Preventive Services Task Force (USPSTF) recommendations for PCa screening, we completed a retrospective comparative analysis of 402 sequential PCa patients diagnosed from 2010 to 2012 (3 years) with 552 PCa patients diagnosed from 2015 to 2017 (3 years). Data was collected on patient age, race, total number of biopsies performed, prostate specific antigen (PSA), Gleason sum score (GSS), and digital rectal examination (DRE). The data was analyzed to determine whether the 2012 USPSTF screening recommendations affected PCa characteristics. Two study groups were defined, Group A and Group B, prior to and after the 2012 USPSTF screening recommendations, respectively. In Group A (pre- 2012 USPSTF recommendations), 567 patients/year underwent a Pbx versus Group B, 398 patients/year, a 30% reduction post-USPSTF. The annual positive Pbx rate for Group A is 134/year versus Group B 184/year, a 37.3% increase post-USPSTF. Group A had high-grade PCa (GSS 7-10) in 51.5% versus Group B in 60.1%, an 8.6% increase post-USPSTF. In Group B, the total number of positive biopsies was increased by 100%. This study shows that in Group B, the Pbx rate decreased by 30% but the annual PCa detection rate increased by 37%. High-grade GSS (7-10) PCa increased by 8.6%. Despite a reduction in the total number of prostate biopsies by 30%, there was a 100% increase in the total number of positive prostate biopsies.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201910256902165ZK.pdf | 793KB | download |