Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study

Journal of Venomous Animals and Toxins including Tropical Diseases

Daiane Dias Ferreira¹  Juliana Tonini Mesquita²  Thais Alves da Costa Silva³ 

[1] Centre for Parasitology and Mycology;Laboratório de Biologia Celular do Instituto Oswaldo Cruz;Universidade Federal de Goiás

关键词: Trypanosoma cruzi;    Drug;    Treatment;    Sertraline;    Drug repurposing;    Drug repositioning;   

DOI  :  10.1186/s40409-018-0165-8

学科分类：过敏症与临床免疫学

来源: SciELO

【 摘 要 】

BackgroundDrug repurposing has been an interesting and cost-effective approach, especially for neglected diseases, such as Chagas disease.

【 授权许可】

CC BY