Novel dental nanocomposites: fabrication and investigation of their physicochemical, mechanical and biological properties

Bulletin of Materials Science

MEHRDAD LOTFI^1,2¹  JALEH BARAR^1,3²  MEHDI JAYMAND^1³ 

[1] Department of Endodontics, Dental Faculty, Tabriz University of Medical Sciences, PO Box 51666-14711, Tabriz, Iran^2;Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, PO Box 14766-51664, Tabriz, Iran^3;Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, PO Box 51656-65811, Tabriz, Iran^1

关键词: Dendritic methacrylate;    dental restorative materials;    biological aspects;    mechanical properties;    physicochemical characteristics.;   

DOI  :  

学科分类：材料工程

来源: Indian Academy of Sciences

【 摘 要 】

The aim of this study was to investigate biological, physicochemical and mechanical characteristics of a series of novel dental restorative nanocomposites that comprise dendritic methacrylate end-caped monomers, triethyleneglycol dimethacrylate (TEGDMA; as diluting monomer) and modified silica nanoparticles (M-SiO$_2$; as inorganic filler). The cytotoxicity effects of the monomers and fabricated nanocomposites were examined against NIH3T3 cells (the standard fibroblast cell line) through MTT and trypan blue cell viability tests, respectively. The antibacterial activities of the monomers were evaluated against Lactobacillus plantarum by standard agar disk diffusion approach.The mechanical properties (flexural strength (FS) and compressive strength (CS)) as well as some physicochemical characteristics such as water sorption (WS), sol fraction (SF) and double bond conversion (DC) were also investigated, and compared with corresponding characteristics of 3M Filtek Z250 as a reference. Thus, the fabricated nanocomposites have potential as dental restorative materials mainly due to their suitable biological, physicochemical and mechanical properties.

【 授权许可】

CC BY