The frequency of human papillomavirus findings in normal oral mucosa of healthy people by PCR

Revista Brasileira de Otorrinolaringologia

Bussoloti Filho, Ivo¹  Carvalho, Maria da Gloria da Costa²  Esquenazi, David³ 

[1] Santa Casa de São Paulo;UFRJ, Brasil;Universidade Federal do Rio de Janeiro

关键词: mouth;    papillomavirus infections;    mouth mucosa.;   

DOI  :  10.1590/S1808-86942010000100013

学科分类：医学（综合）

来源: Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial

【 摘 要 】

The human papillomavirus (HPV) is a DNA virus, which belongs to papillomaviridae family, being of low and high risk, which infect the skin and mucous membranes and can induce benign and malign tumor formation. In the oral mucosa they have been associated with oral papilloma, focal epithelial hyperplasia, leucoplakia and oral neoplasia. AIM: to study the frequency of HPV finding in oral mucosa of normal people. MATERIALS AND METHODS: Prospective study, cross-sectional cohort. One hundred volunteers, young adults, healthy, aged between 20 and 31 years, university students with no history, no complains, without oral or oropharyngeal lesions. They were submitted to a questionnaire with questions regarding HPV infection epidemiology. The samples were harvested by brushing and analyzed by PCR. RESULTS: The results were negative for HPV in all samples. CONCLUSION: It seems we had high social and economical class individuals, with nutrition rich in carotenoyds and vitamin C, low smoking and alcohol consumption and heterosexual habits with predominant monogamy and regular use of condoms.

【 授权许可】

CC BY