Pleomorphic adenoma of the mandibular salivary gland in a captive African pygmy hedgehog (Atelerix albiventris)

The Journal of Veterinary Medical Science

Du-Min GO¹  Sang-Ho WOO² 

[1] Department of Veterinary Pathology and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea;National Cancer Center, Goyang 10408, Republic of Korea

关键词: hedgehog;    immunohistochemistry;    pleomorphic adenoma;    salivary gland;   

DOI  :  10.1292/jvms.18-0531

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

A 3.9-year-old female African pygmy hedgehog (Atelerix albiventris) had a firm, tan-colored mass with an uneven surface arising from the mandibular salivary gland. A histopathologic examination revealed that the mass was composed of neoplastic proliferation of epithelial and spindle cells. The neoplastic spindle cells showed positive for vimentin, smooth muscle actin, calponin and cytokeratin 14 and, negative for cytokeratin 19, suggesting that spindle cells were derived from myoepithelial cells. Based on the histological findings and immunohistochemistry results, the mass was diagnosed as pleomorphic adenoma. Pleomorphic adenoma is the most common benign tumor found in human salivary glands, but it is rare in animals. To the best of our knowledge, this is the first report of pleomorphic adenoma in hedgehogs.

【 授权许可】

Unknown