Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease

Radiology and Oncology

Natasa Smrekar^1¹  David Drobne^1² 

[1] Department of Gastroenterology and Hepatology, Ljubljana, Slovenia^1;Institutes of Microbiology and Immunology, Faculty of Medicine, Ljubljana, Slovenia^2

关键词: inflammatory bowel disease;    dendritic cells;    tumor necrosis factor-alpha inhibitors;    colon cancer;   

DOI  :  10.2478/raon-2018-0045

学科分类：肿瘤学

来源: Onkoloski Institut Ljubljana / Institute of Oncology Ljubljana

【 摘 要 】

BackgroundDendritic cells play crucial roles in the control of inflammation and immune tolerance in the gut. We aimed to investigate the effects of tumor necrosis factor alpha (TNFa) inhibitors on intestinal dendritic cells in patients with inflammatory bowel disease and the potential role of intestinal dendritic cells in predicting the response to treatment.

【 授权许可】

Unknown