Uso de ácido tranexámico en las hemorragias

Revista Cubana de Cirugía

Piamo Morales, Alberto J.¹  Rojas, Mayra A.² 

[1] Hospital Clínico Quirúrgico Docente Joaquín Albarrán, La Habana, Cuba;Hospital Ginecobstétrico América Arias, La Habana, Cuba

关键词: tranexamic acid;    trauma;    acute hemorrhage;    anti-fibrinolysis.;   

DOI  :  

学科分类：外科医学

来源: SciELO

【 摘 要 】

According to the present scientific evidence, the administration of a simple economic treatment with anti-fibrinolytic properties such as the tranexamic acid can reduce the blood loss after trauma, and decrease the risk associated to blood transfusions. Tranexamic acid is a synthetic derivative of lysine with pure anti-fibrinolytic activity. Its mechanism of action is based on the joining to the plasminogen lysine bond, which blocks the binding of fibrin to the activating complex of plasminogen-plasmin. This review was aimed at describing the results of the use of tranexamic acid based on available evidence. To this end, a literature search was made in PubMed, SciELO and Clinical Keys databases.

【 授权许可】

CC BY-NC