The Benefit of Mirtazapine in the Treatment of Progressive Multifocal Leukoencephalopathy in a Young HIV-positive Patient: A Case Report

Innovations in Clinical Neuroscience

Jorge Mira¹  Hugo Soval²  Carola Mullins³ 

[1] Dr. Miranda is with the Paul Foster School of Medicine;Dr. Tonarelli is with the Department of Psychiatry all with Texas Tech University Health Sciences Center in El Paso, Texas.;Drs. Mullins, Sandoval, and Ramos-Duran are with the Department of Radiology

关键词: Progressive multifocal leukoencephalopathy (PML);    acquired immunodeficiency syndrome (AIDS);    human immunodeficiency virus (HIV);    mirtazapine;    highly active antiretroviral therapy (HAART);   

DOI  :  

学科分类：精神健康和精神病学

来源: Matrix Medical Communications, LLC

【 摘 要 】

Highly active antiretroviral therapy is well-established in the treatment of human immunodeficiency virus (HIV)-positive patients. Nonadherence with therapy regimens often leads to the occurrence of opportunistic infections that further complicate treatment and challenge the treating physician. We report a young HIV-positive patient who suffered from progressive multifocal leukoencephalopathy caused by the human John Cunningham virus and showed objective clinical improvement after adding mirtazapine to the treatment regimen, an observation that is supported by the emerging literature.

【 授权许可】

Unknown