Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals

Radiology and Oncology

Borut Kobal^1¹  Matija Barbic^1²  Marco Noventa^2³  Branko Cvjeticanin^1⁴ 

[1] Ljubljana, Slovenia^1;Ljubljana, Slovenia^4;Padua, Italy^2;Varese, Italy^3

关键词: epithelial ovarian cancer;    advanced stage;    primary debulking surgery;    interval debulking surgery;    neoadjuvant chemotherapy;    adjuvant chemotherapy;    overall survival;    progression free survival;   

DOI  :  10.2478/raon-2018-0030

学科分类：肿瘤学

来源: Onkoloski Institut Ljubljana / Institute of Oncology Ljubljana

【 摘 要 】

BackgroundThe aim of the study was to analyze the overall survival (OS) and progression free survival (PFS) of patients with high grade and advanced stage epithelial ovarian cancer (EOC) with at least 60 months of follow-up treated in a single gynecologic oncology institute. We compared primary debulking surgery (PDS) versus neoadjuvant chemotherapy plus interval debulking surgery (NACT + IDS) stratifying data based on residual disease with the intent to identify the rationale for therapeutic option decision and the role of laparoscopic evaluation of resectability for that intention.

【 授权许可】

Unknown