The effects of saline water consumption on the ultrasonographic and histopathological appearance of the kidney and liver in Barki sheep

The Journal of Veterinary Medical Science

Attia EISSA¹  Mohamed GHANEM²  Mohamed ZEINELDIN³ 

[1] Department of Animal Health Desert Research Center Materia, Cairo-11311, Egypt;Department of Animal Medicine, College of Veterinary Medicine, Benha University, Benha-13511, Egypt;Integrated Food Animal Management Systems, Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Champaign-61802, IL, U.S.A.

关键词: histopathology;    kidney;    liver;    sheep;    ultrasonography;   

DOI  :  10.1292/jvms.17-0596

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

The objective of this study was to evaluate the impact of varying degrees of water salinity on the ultrasonographical and histopathological appearance of the liver and kidneys in Barki sheep. Thirty Barki sheep (initial weight, 29.48 ± 0.81 kg) were allocated into three groups (n=10 per group) based on the type of drinking water for 9 months: the tap water (TW) group (350 ppm total dissolved solids [TDS]); the moderate saline water (MSW) group (4,557 ppm TDS); and the high saline water (HSW) group (8,934 ppm TDS). After 9 months, the body weight was significantly decreased in sheep subjected to MSW (P=0.0347) and HSW (P=0.0424). Alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, urea, and creatinine were significantly increased (P<0.05) in sheep subjected to MSW and HSW. Ultrasonographic examination of the right and left kidneys revealed an increased length of both kidneys with crystal formation, particularly in male sheep. Ultrasonographic examination of the liver showed hyperechogenic dots varying in size and number between males and females. Histopathological examination of kidney revealed significant changes in both MSW and HSW groups such as hyaline matrix formation, atrophied glomerular tufts, and intramedullary congestion. Histopathological examination of the liver revealed slight fatty liver changes, slight fibrosis around the bile duct, massive inflammatory cell infiltration and vacuolar changes of hepatocytes in both MSW and HSW groups. In conclusion, water salinity negatively affects the body weight, liver and kidney appearance of Barki sheep and thus sheep production.

【 授权许可】

Unknown