A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network

Basic and applied myology

Manuela Lavorato¹  Clara Franzini-Armstrong¹  Ramesh Iyer² 

[1] Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA;Division of Cardiology, Children Hospital of Philadelphia, Philadelphia, PA

关键词: Ultrastructure;    Sarcoplasmic reticulum;    Transverse tubules;    Triads;   

DOI  :  10.4081/ejtm.2019.8264

学科分类：农业科学（综合）

来源: Pagepress

【 摘 要 】

Using a variety of technical approaches, we have detected the presence of continuous triads that cover the entire length of T tubules in the main white body muscles of several small fish. This is in contrast to the discontinuous association of sarcoplasmic reticulum with T tubules in the red muscles from the same fish as well as in all other previously described muscles in a large variety of skeletal muscles. We suggest that continuous triads are permissible only in muscle fibers that are not normally subject to significant changes in sarcomere length during normal in vivo activity, as is the case for white muscles in the trunk of fish.

【 授权许可】

CC BY