Proliferative verrucous leukoplakia: diagnosis, management and current advances

Revista Brasileira de Otorrinolaringologia

Capella, Diogo Lenzi¹ 

[1] Universidade Federal de Santa Catarina, Florianopolis, Brazil

关键词: Leukoplakia oral;    Leukoplakia;    Proliferative verrucous leukoplakia;    Oral cancer;    Squamous cell carcinoma;    Head and neck cancer.;   

DOI  :  10.1016/j.bjorl.2016.12.005

学科分类：医学（综合）

来源: Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial

【 摘 要 】

Introduction: Proliferative verrucous leukoplakia is a multifocal and progressive lesion of the oral mucosa, with unknown etiology, and commonly resistant to all therapy attempts with frequent recurrences. It is characterized by a high rate of oral squamous cell carcinoma and verrucou carcinoma transformations.Objective: To analyze the studies about Proliferative verrucous leukoplakia and develop a concise update.Methods: A Pubmed search identifying studies (laboratory research, case series and reviews of literature) that examined patients with Proliferative verrucous leukoplakia was realized.Results: There are not enough studies about Proliferative verrucous leukoplakia in the literature. The few found studies not present a consensus about its etiology and diagnosis criteria. Although several treatment strategies have been proposed, most of them still show a high recurrence rate.Conclusion: More research about Proliferative verrucous leukoplakia is necessary to understand and treat this disease.

【 授权许可】

CC BY