Haplotypes of P2RX7 Gene Polymorphisms are Associated with both Cold Pain Sensitivity and Analgesic Effect of Fentanyl

Molecular Pain

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[1] Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan;Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;Department of Anesthesiology & Pain Medicine, Juntendo University School of Medicine, Tokyo, Japan;Department of Dental Anesthesiology, Tokyo Dental College, Tokyo, Japan;Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;

关键词: P2X receptor;    ATP;    Purinergic receptor;    Single-nucleotide polymorphism;    Pain;    Fentanyl;    Cold pain;    Haplotype analysis;    Perioperative analgesia;   

DOI  :  10.1186/1744-8069-10-75

来源: publisher

【 授权许可】

CC BY