Screening for posttraumatic stress disorder in ARDS survivors: validation of the Impact of Event Scale-6 (IES-6)

Critical Care

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[1] 0000 0001 2171 9311, grid.21107.35, Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0001 2171 9311, grid.21107.35, Outcomes After Critical Illness and Surgery (OACIS) Group, Johns Hopkins School of Medicine, Baltimore, MD, USA;0000 0004 0609 0182, grid.414785.b, Department of Medicine, Pulmonary and Critical Care Division, Intermountain Medical Center, Murray, UT, USA;0000 0004 0460 774X, grid.420884.2, Center for Humanizing Critical Care, Intermountain Health Care, Murray, UT, USA;0000 0004 1936 9115, grid.253294.b, Neuroscience Center and Psychology Department, Psychology Department and Neuroscience Center, Brigham Young University, Provo, UT, USA;

关键词: Posttraumatic stress disorder;    Critical care;    Survivorship;    Validation studies;    Mental health;    Psychometric;   

DOI  :  10.1186/s13054-019-2553-z

来源: publisher

【 摘 要 】

BackgroundPosttraumatic stress disorder (PTSD) symptoms are common in acute respiratory distress syndrome (ARDS) survivors. Brief screening instruments are needed for clinical and research purposes. We evaluated internal consistency, external construct, and criterion validity of the Impact of Event Scale-6 (IES-6; 6 items) compared to the original Impact of Event Scale—Revised (IES-R; 22 items) and to the Clinician Administered PTSD Scale (CAPS) reference standard evaluation in ARDS survivors.MethodsThis study is a secondary analysis from two independent multi-site, prospective studies of ARDS survivors. Measures of internal consistency, and external construct and criterion validity were evaluated.ResultsA total of 1001 ARDS survivors (51% female, 76% white, mean (SD) age 49 (14) years) were evaluated. The IES-6 demonstrated internal consistency over multiple time points up to 5 years after ARDS (Cronbach’s alpha = 0.96; 95% confidence interval (CI) 0.94 to 0.97). The IES-6 demonstrated stronger correlations with related constructs (e.g., anxiety and depression; |r| = 0.32 to 0.52) and weaker correlations with unrelated constructs (e.g., physical function and healthcare utilization measures (|r| = 0.02 to 0.27). Criterion validity evaluation with the CAPS diagnosis of PTSD in a subsample of 60 participants yielded an area under receiver operating characteristic curve (95% CI) of 0.93 (0.86, 1.00), with an IES-6 cutoff score of 1.75 yielding 0.88 sensitivity and 0.85 specificity.ConclusionsThe IES-6 is reliable and valid for screening for PTSD in ARDS survivors and may be useful in clinical and research settings.

【 授权许可】

CC BY