Sterol regulatory element‐binding protein‐1c orchestrates metabolic remodeling of white adipose tissue by caloric restriction

Aging Cell

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[1] Faculty of Bioresource Sciences, Akita Prefectural University, Shimoshinjo, Nakano, Akita, 010‐0195, Japan;Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278‐8510, Japan;Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278‐8510, Japan;Translational Research Center, Research Institute of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278‐8510, Japan;Translational Research Center, Research Institute of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278‐8510, Japan;Department of Internal Medicine Research, Sasaki Institute, Sasaki Foundation, 2‐2 Kandasurugadai, Chiyoda‐ku, Tokyo, 101‐0062, Japan;Translational Research Center, Research Institute of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278‐8510, Japan;Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, 1‐12‐4 Sakamoto, Nagasaki, 852‐8523, Japan;

关键词: CR;    white adipose tissue (WAT);    mitochondria biogenesis;    oxidative stress;    sterol regulatory element binding protein‐1c (Srebp‐1c);    peroxisome proliferator‐activated receptor gamma coactivator‐1α (Pgc‐1α);   

DOI  :  10.1111/acel.12576

来源: publisher

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