Exploring Pharmacological Activities and Signaling of Morphinans Substituted in Position 6 as Potent Agonists Interacting with the μ Opioid Receptor

Molecular Pain

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[1] Department of Medical Sciences, Section of Pharmacology and Italian Institute of Neuroscience, University of Ferrara, Ferrara I-44121, Italy;Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, Innsbruck A-6020, Austria;Department of Pharmaceutical Sciences, University of Maryland, School of Pharmacy, Baltimore, MD 21201, USA;Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298-0613, USA;Department of Pharmacology, University of Michigan Medical School, 1301 MSRB III, 1150 West MedicalCenter Drive, Ann Arbor, MI48109-5632, USA;

关键词: Opioid receptors;    Agonist;    Morphine;    Oxycodone;    Pain;    Analgesia;    Signaling;    G protein;    Calcium mobilization;   

DOI  :  10.1186/1744-8069-10-48

来源: publisher

【 授权许可】

CC BY