Biofilm and hemagglutinin formation: a Hallmark for drug resistant uropathogenic Escherichia coli

BMC Research Notes

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[1] 0000 0001 1539 8988, grid.30820.39, Department of Internal Medicine, College of Health Sciences, Mekelle University, Mekelle, Tigray, Ethiopia;0000 0001 1539 8988, grid.30820.39, Department of Microbiology and Immunology, College of Health Sciences, Mekelle University, Mekelle, Tigray, Ethiopia;0000 0001 1539 8988, grid.30820.39, School of Public Health, College of Health Sciences, Mekelle University, Mekelle, Tigray, Ethiopia;

关键词: UPEC;    Biofilm;    Drug resistance;    UTI;   

DOI  :  10.1186/s13104-019-4382-1

来源: publisher

【 摘 要 】

ObjectiveUrinary tract infection (UTI) is one of the most frequent disease encounters in pregnant mothers, and the most drug resistant, biofilm and hemagglutinin producer Uropathogenic Escherichia coli (UPEC) is the major etiologic agent. Therefore, the aim of this study was to assess the association between the antimicrobial resistance, and biofilm and hemagglutinin production of Uropathogenic Escherichia coli.ResultsUTI among the study participants was 27.3%; and UPEC was found the major etiologic agent followed by coagulase negative staphylococcus. Risk factors, previous history of catheterization and previous history of UTI were found significantly associated with UTI, recurrent UTI, drug resistance and biofilm formation. Of the tested antibiotics, nitrofurantoin was the most effective drug for UPEC. Nearly 100% of the biofilm producers were resistant to norfloxacin, cotrimoxazole, and gentamicin.

【 授权许可】

CC BY