The role of miR-320a and IL-1β in human chondrocyte degradation

Bone & Joint Research

关键词: Osteoarthritis (OA);    microRNA-320a;    PBX3;    Extracellular matrix;    NF-κB;   

DOI  :  10.1302/2046-3758.64.BJR-2016-0224.R1

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

ObjectivesThis study aimed to explore the role of miR-320a in the pathogenesis of osteoarthritis (OA).MethodsHuman cartilage cells (C28/I2) were transfected with miR-320a or antisense oligonucleotides (ASO)-miR-320a, and treated with IL-1β. Subsequently t

【 授权许可】

CC BY-NC