Effects of a phosphocitrate analogue on osteophyte, subchondral bone advance, and bone marrow lesions in Hartley guinea pigs

Bone & Joint Research

关键词: Osteoarthritis;    Subchondral bone;    Bone marrow lesions;    MMP13;    Phosphocitrate;   

DOI  :  10.1302/2046-3758.72.BJR-2017-0253

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

Objectives The objectives of this study were: 1) to examine osteophyte formation, subchondral bone advance, and bone marrow lesions (BMLs) in osteoarthritis (OA)-prone Hartley guinea pigs; and 2) to assess the disease-modifying activity of an orally admin

【 授权许可】

CC BY-NC