Can zinc protect cells from the cytotoxic effects of cobalt ions and nanoparticles derived from metal-on-metal joint arthroplasties?

Bone & Joint Research

关键词: Cobalt cytotoxicity;    Protective effects;    Zinc;    Cobalt nanoparticles;    Cobalt ions;   

DOI  :  10.1302/2046-3758.612.BJR-2016-0137.R2

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

Objectives Recently, high failure rates of metal-on-metal (MOM) hip implants have raised concerns of cobalt toxicity. Adverse reactions occur to cobalt nanoparticles (CoNPs) and cobalt ions (Co2+) during wear of MOM hip implants, but the toxic mechanism i

【 授权许可】

CC BY-NC