Intra-articular injection of Torin 1 reduces degeneration of articular cartilage in a rabbit osteoarthritis model

Bone & Joint Research

关键词: Osteoarthritis;    Articular cartilage degradation;    Intra-articular injection;    Torin 1;    Autophagy;   

DOI  :  10.1302/2046-3758.56.BJR-2015-0001

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

ObjectivesRecent studies have shown that systemic injection of rapamycin can prevent the development of osteoarthritis (OA)-like changes in human chondrocytes and reduce the severity of experimental OA. However, the systemic injection of rapamycin leads t

【 授权许可】

CC BY-NC