Silencing of microRNA-138-5p promotes IL-1β-induced cartilage degradation in human chondrocytes by targeting FOXC1

Bone & Joint Research

关键词: MicroRNA-138;    IL-1β;    osteoarthritis;    cartilage degradation;    FOXC1;   

DOI  :  10.1302/2046-3758.510.BJR-2016-0074.R2

学科分类：骨科学

来源: British Editorial Society Of Bone And Joint Surgery

【 摘 要 】

ObjectivesOsteoarthritis (OA) is characterised by articular cartilage degradation. MicroRNAs (miRNAs) have been identified in the development of OA. The purpose of our study was to explore the functional role and underlying mechanism of miR-138-5p in inte

【 授权许可】

CC BY-NC