Single dose of secnidazole treatment against naturally occuring Giardia duodenalis infection in Sakiz lambs

Revista MVZ Cordoba

Aysul, Nuran¹  Eren, Hasan¹  Aldemir, Osman S.¹  Ulutas, Bulent²  Voyvoda, Huseyin²  Ural, Kerem² 

[1] Adnan Menderes University, Turkey;University of Adnan Menderes, Turkey

关键词: Clinics;    evaluation;    secnidazol;    lamb.;   

DOI  :  

学科分类：兽医学

来源: Universidad de Cordoba * Facultad de Medicina Veterinaria y Zootecnia

【 摘 要 】

Objetive. The purposes of this study were to determine whether secnidazole administered at a single dose of 10 mg/kg, orally, lessens or eliminates Giardia cyst shedding, and to validate the benefit of secnidazole treatment on clinical signs and faecal consistency in lambs naturally infected with Giardia duodenalis. Materials and methods. To this extent weaned 12 weeks of age lambs were selected and randomly assigned into two groups based on placebo (group C, n=7 untreated control group) or treatment (group S, n=10 lambs treated with a single dose of secnidazole at 10 mg/kg). Results. On days 0 and 10, before and after treatment, respectively, reduction in cyst excretion was determined. The faecal consistency and general health were recorded at each sampling day. Conclusions. During the study there was a high (99.98%) reduction in cyst excretion in the secnidazol treatment group compared to the positive control group on day 10, resulting in a significant (p<0.001) reduction, making secnidazole highly effective treatment option.

【 授权许可】

Unknown